Crystal structure of the class D β-lactamase OXA-40
نویسندگان
چکیده
منابع مشابه
Crystal structure of the class D beta-lactamase OXA-10.
We report the crystal structure of a class D beta-lactamase, the broad spectrum enzyme OXA-10 from Pseudomonas aeruginosa at 2.0 A resolution. There are significant differences between the overall fold observed in this structure and those of the evolutionarily related class A and class C beta-lactamases. Furthermore, the structure suggests the unique, cation mediated formation of a homodimer. K...
متن کاملOXA-253, a variant of the carbapenem-hydrolyzing class D β-lactamase OXA-143 in Acinetobacter baumannii.
The carbapenem-hydrolyzing class D β-lactamase OXA-253 was identified in an Acinetobacter baumannii clinical isolate belonging to sequence type 113 (ST113) in Brazil. OXA-253 shares 93.8% amino acid identity with OXA-143. The blaOXA-253 gene is located on a ca. 20-kb plasmid. The genetic environment of the blaOXA-253 gene shares the highest identity with ubiquitous GR2 group plasmids usually ca...
متن کاملDetection of OXA-370, an OXA-48-related class D β-lactamase, in Enterobacter hormaechei from Brazil.
Jorge L. M. Sampaio, Vanessa B. Ribeiro, Juliana Coutinho Campos, Franciéli P. Rozales, Cibele M. Magagnin, Diego R. Falci, Renato Cassol F. da Silva, Micheline G. Dalarosa, Daniela I. Luz, Fabiane J. Vieira, Laura C. Antochevis, Afonso Luis Barth, Alexandre P. Zavascki Departamento de Análises Clínicas e Toxicológicas—Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, B...
متن کاملChromosome-Encoded Class D -Lactamase OXA-23 in Proteus mirabilis
Chromosome-Encoded Class D -Lactamase OXA-23 in Proteus mirabilis R. Bonnet,* H. Marchandin, C. Chanal, D. Sirot, R. Labia, C. De Champs, E. Jumas-Bilak, and J. Sirot Laboratoire de Bactériologie, Faculté de Médecine, 63001 Clermont-Ferrand Cedex, Laboratoire de Bactériologie, Hôpital Arnaud de Villeneuve, 34295 Montpellier Cedex 5, UMR 175, CNRS-MNHN, 29000 Quimper, Laboratoire de Bactériologi...
متن کاملdistribution of oxa-type class d β-lactamase genes among nosocomial multi drug resistant acinetobacter baumannii isolated in tehran hospitals
conclusions the present study showed that bla oxa-23-like was the most frequent carbapenemase identified among carbapenem-resistant a. baumannii isolated in tehran hospitals. evaluation of antibiotic resistance genes in a. baumannii, is necessary to control further dissemination of these antibiotic resistant genes. results results showed that 123 of 131 (93.89%) acinetobacter species, possessed...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2011
ISSN: 0108-7673
DOI: 10.1107/s0108767311087873